Séminaire PhilSciCog

Nous aurons le plaisir d’entendre Catherine Belzung, qui est professeur en neurosciences à l’Université de Tours. Ses thématiques de recherche se déclinent en plusieurs thèmes, tous centrés autour de la neurobiologie de la dépression majeure et de l'étude du mécanisme d'action des antidépresseurs, en utilisant une approche pluridisciplinaire, suscitant le dialogue entre spécialistes de différentes disciplines et en intégrant des méthodologies de différents champs de la connaissance (neuroscience, psychiatrie, philosophie, physique, économie).

Titre : Neurostimulation in Psychiatry: moving toward circuit-based models of mental illness

Résumé : Neurostimulation of targeted brain regions has emerged as a novel therapeutic approach to induce remission in patients with various psychiatric disorders. This strategy encompasses several modalities, including transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), deep brain stimulation (DBS), and transcranial focused ultrasound neurostimulation (tFUS), all of which aim to modulate dysfunctional neural circuits and restore activity toward physiological ranges. While the clinical efficacy of these techniques is increasingly documented, the mechanisms underlying their effects—beyond immediate changes in regional excitability—remain incompletely understood. Further, neurostimulation represents not only a technical advance, but also a conceptual shift in psychiatry, moving from interventions aimed at modulating neurotransmission or cognition toward circuit-based models of mental illness. This conference aims at  clarify the mechanisms of action of neurostimulation across multiple levels of biological integration, ranging from large-scale neural circuits to cellular and subcellular processes, before exploring emerging innovative modalities based on that concept. Finally, it will address the conceptual challenges that accompany the translation of circuit-based models from neuroscience to clinical psychiatry.

Lien Zoom
ID de réunion: 950 6108 6376
Code secret: 535047